Lehae

 

Kolajeneke karolo e kgolo ya matrix ya kantle ho sele (ECM), e fumanwang haholo-holo letlalong la motho, masapong, lefufurung, menong, di-tendon, di-ligaments le methapong ya madi. Hape ke protheine ya bohlokwa ya sebopeho sa dinama tse hokahaneng.

Collagen ke karolo e kholo ea dermis ea letlalo la motho. Hammoho le elastin e nyane, e etsa marang-rang a tloaelehileng a likhoele tsa collagen, e leng se fang letlalo ho tenyetseha le ho tiea 'me se lumella lera la epidermal ho tsamaisa mongobo.

Leha ho le jwalo, mabaka a kang botsofali, mahlasedi a UV, ho tsuba le mekgwa e sa pheleng hantle ya bophelo a etsa hore collagen e fokotsehe. Ha collagen e lahleha ka bongata, matshwao a botsofali a kang ho lahlehelwa ke ho tenyetseha ha letlalo, ho tetebela, makukuno, mmala, ho oma, letlalo le makukuno le letlalo le bonolo a hlaha butle-butle.

Kahoo, ha collagen e ntse e fokotseha, na lihlahisoa tsa collagen tse nooang li ka liehisa ts'ebetso ea botsofali?

Na li-peptide tsa collagen tse molomong li ka monngoa ke 'mele?

Lihlahisoa tse tloaelehileng tsa collagen tse rekisoang li bua ka li-peptide tsa collagen, eseng collagen.

KolajeneLi-peptide ke motsoako oa li-peptide tse nang le boima bo tlase ba limolek'hule tse nang le boima bo tloaelehileng ba limolek'hule ba 2000 ho isa ho 10,000 Da tse hydrolyzed ho tsoa ho collagen (300,000 Da). Ha li bapisoa le collagen e nang le boima bo phahameng ba limolek'hule, li-peptide tsa collagen li na le boima bo bonyenyane ba limolek'hule 'me li sileha habonolo le ho monngoa.

Ho phaella moo, dipeptide le di-tripeptide tse fumanehang ka har'a li-peptide tsa collagen li tsamaisoa ka ho toba 'me li monngoa e le li-peptide ke protheine ea oligopeptide transporter (PepT1) e teng liseleng tsa epithelial tsa mala a manyane. Li ka lebisoa libakeng tse itseng 'meleng bakeng sa ts'ebetso ea baeloji le katleho.

Watanabe-Kamiyama M. le ba bang ba ile ba metsa li-peptide tsa collagen tse nang le lebitso la 14C lithong tse fapaneng tsa litoeba 'me ba bona kabo eali-peptide tsa collagen.

Phuputso e bontšitse hore li-peptide tsa collagen tse nooang li ne li abeloa litho tsa bohlokoa 'meleng oohle ka mor'a tšilo ea lijo le ho monngoa, 'me li ne li bolokiloe ka ho khetheha liseleng tse nang le collagen e ngata, haholo-holo letlalong, ka mor'a nako e itseng.

Na Li-peptide tsa Collagen tsa Molomo li ka Ntlafatsa Maemo a Letlalo?

Lilemong tsa morao tjena, lithuto tse ngata li tiisitse liphello tse molemo tsa li-peptide tsa collagen tse nooang ho liehiseng botsofali ba letlalo le ho nchafatsa letlalo.

Bafuputsi ba khethile baithaopi ba 64 ba pakeng tsa lilemo tse 40 le 60 ho nka 1000 mg ea li-peptide tsa collagen tse nang le boima bo tlase ba limolek'hule ka molomo letsatsi le letsatsi bakeng sa libeke tse 12 'me ba fumane hore kamora libeke tse 6 tsa ho noa, metsi a letlalo a ntlafetse haholo, 'me kamora libeke tse 12, makhopho le ho tenyetseha ha letlalo li ntlafetse, tse bontšang litlamorao tsa ho thibela botsofali. Liphetho li bontšitse ntlafatso e kholo ea ho boloka mongobo oa letlalo kamora libeke tse 6 tsa ho noa le phello ea ho thibela botsofali kamora libeke tse 12.